In the late 19th and early 20th centuries, Ashmyany was a dynamic shtetl on the Vilna borderlands. The Great synagogue took shape during this period, with community fundraising recorded in 1857 and a ceremonial opening noted in 1902. Externally austere, it encloses a tall inner dome, an ingenious response to historic height restrictions on synagogues. The building once anchored a larger shulhoyf (synagogue courtyard complex) of nine prayer spaces and served as the spiritual and social heart of the community.
Closed in 1940 and repurposed during the Soviet era, the synagogue came close to being demolished in the 1980s but was miraculously preserved. Today, as Jewish heritage across the region continues to disappear, it stands as a rare surviving witness, though t its condition is critical and demands urgent preservation.